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Arora, Manju
- Nanobacteria - Present Status and Role in Human Diseases
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PDF Views:219
Authors
Affiliations
1 Department of Microbiology, Gian Sagar Medical College & Hospital, Punjab, 140601, IN
2 Department of Microbiology, GianSagar Medical College and Hospital, Banur, Punjab, IN
1 Department of Microbiology, Gian Sagar Medical College & Hospital, Punjab, 140601, IN
2 Department of Microbiology, GianSagar Medical College and Hospital, Banur, Punjab, IN
Source
SMU Medical Journal, Vol 2, No 2 (2015), Pagination: 241-248Abstract
The status of nanobacteria has been controversial, with some researchers suggesting they are a new class of living organism and others attributing to them a simpler, abiotic nature. They appear to be ubiquitous entities found in living and non-living substrates. Research has suggested that nanobacteria could be the cause of a wide variety of diseases, from kidney stones to atherosclerosis.Full Text
References
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- Current Concept of New-Delhi Metallo Beta Lactamases (NDM)
Abstract Views :227 |
PDF Views:173
Authors
Ravikant
1,
Satish Gupte
2,
Prerna Aggarwal
1,
Maninder Kaur
3,
Ashwini Manhas
1,
Manju Arora
1,
Mrinangka Dev
1
Affiliations
1 Department of Microbiology, Gian Sagar Medical College & Hospital, Banur, Punjab, IN
2 Gian Sagar Medical College & Hospital, IN
3 Department of Microbiology, Gian Sagar Medical College & Hospital, Banur, Punjab
1 Department of Microbiology, Gian Sagar Medical College & Hospital, Banur, Punjab, IN
2 Gian Sagar Medical College & Hospital, IN
3 Department of Microbiology, Gian Sagar Medical College & Hospital, Banur, Punjab
Source
SMU Medical Journal, Vol 1, No 2 (2014), Pagination: 88-101Abstract
The emergence of superbugs intermittently has always been a global threat for control and treatment of infectious disease caused by them over many decades which influence human population with their mutated genetic make-up and mechanics of resistance. However, bacteria have been developing resistance to antibiotics since they were introduced in 1930s. From the year 1961 till date, among some of the more common superbugs are methicillin-resistant Staphylococcus aureus (MRSA) and drug resistant tuberculosis (MDR-TB and XDR-TB). The latest superbug encodes the gene for New Delhi metallo-beta-lactamase (NDM-1) is an enzyme that can hydrolyze and inactivate carbapenems, which are used as a last resort for the treatment of multi-resistant bacterial infection. Escherichia coli and Klebsiella pneumoniae commonly expresses the gene for NDM-1 moreover NDM-2 in Acinetobacter baumannii, NDM-4, NDM-5, NDM- 6, NDM-7 and NDM-8 from E.coli and other Enterobacteriaceae also have been reported. Research is on to develop new classes of antibiotic to handle these threats and it is worrying as there are very limited therapeutics available in the development pipeline that works effectively in the current situation.Full Text